News It’s happening again: COVID-19 cases are back on the rise. There are 3 main reasons why. May 18, 2022May 19, 2022 Elizabeth Weise, USA TODAY Comments Off on It’s happening again: COVID-19 cases are back on the rise. There are 3 main reasons why. COVID-19 infections are up, driven by new variants, waning immunity from vaccines and past infections and fewer people masking, health officials say.